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I have a problem pronouncing a uvular trill when lying on my side (I mean completely horizontal, without a tilt), but normally I can trill for over 20 seconds. Even if I start trilling and move my body in a horizontal position, it stop sounding like a trill.
I think I know what's going on, the uvula hang in the wrong direction and that might be the cause.
I keep practicing till I get the hang of it.
Articulation can be affected by gravity. Jaw movement and tongue position depends on neural feedback mechanisms to determine if the target has been reached. This doesn't absolutely limit ability to make certain sounds, but it can make it more difficult to articulate correctly. A "simple" test is to try talking upside down: it can be done, but it takes a little while to readjust. Respiration (thus phonation) is also affected by having your giblets on top of your lungs, but again you can learn to adjust.
An interesting experiment would be studying acquisition of new sounds (e.g. Arabic ʕ, Lushootseed ƛ', Hungarian gy, Khoisan clicks), when subjects practice the sound only when inverted. I predict initial difficulties in articulation when subjects are allowed to make these sounds when standing.
I think , of all the IPA consonants and vowels, the ones with association to air would be a bit difficult to pronounce in the same way, 'cause changing gravity (in drastic way) can change air thickness. E.g. Implosives, Explosives, Aspirations, Clicks etc.
